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When loser Duke, who has screwed up every hair-brained scheme he's ever come up with, accidentally falls off a cruise ship and wakes up on a mysteriously abandoned, top secret government island, he discovers that it's overrun with mutants and monsters from a failed 1980s DARPA "super soldier" project to stop the 2nd Cold War.
James Schrader
Duke
Juliana Harkavy
Dyanna
Harland Williams
Sam
James Marsters
Reggie
Spencer Grammer
Moon
Harry Lennix
General Dregg
John DiMaggio
Colonel Fergusen
Michael 'Indy' Johns
Barry
Maurice LaMarche
Dr. Oculus
Dana Snyder
Pete
LeeAnna Vamp
Midnight
Will Friedle
El Feo
J. LaRose
Flanagan
Barry Bostwick
Potus
Christopher Sabat
Jerry
Matt Zunich
Luis
Gigi Edgley
Love Theme Performer
Kristina Klebe
Liliana
Sarah French
Lacy
Heather Nichols
Tilda Topper
Noel Cox
Ben Bottomsmouth
Atif Myers
Rodrick
Dia Frampton
Security Guard Casey
Rubin Ervin
Party Phil
Tara Dane
Alaurha
Milynn Sarley
Bernadette
André Gower
Agent Chesnic
Kira Omans
Sgt. Jaxx
Colton Wheeler
Private Peck
Tyler Gallant
Private Johnson
Kelly McDevitt
Debbie Peck
Melissa Gruver
Duke's Mom
Randy Molnar
Duke's Dad
A.R. Björklund
Vomiting Passenger
Keenan McClelland
Gort