Michael Fassbender
David / Walter
Katherine Waterston
Daniels
Billy Crudup
Oram
Danny McBride
Tennessee
Demián Bichir
Lope
Carmen Ejogo
Karine
Jussie Smollett
Ricks
Callie Hernandez
Upworth
Amy Seimetz
Faris
Nathaniel Dean
Hallett
Alexander England
Ankor
Benjamin Rigby
Ledward
Uli Latukefu
Cole
Tess Haubrich
Rosenthal
Lorelei King
Mother (voice)
Goran D. Kleut
Xenomorph / Neomorph
Andrew Crawford
Neomorph
Tom O'Sullivan
David / Walter Double
James Franco
Jacob Branson (uncredited)
Guy Pearce
Peter Weyland (uncredited)