Horst Buchholz
Marco Polo
Anthony Quinn
Kublai Khan
Orson Welles
Akerman, Marco's Teacher
Bruno Cremer
Guillaume de Tripoli, a Knight Templar
Omar Sharif
Sheik Alla Hou
Robert Hossein
Prince Nayam
Akim Tamiroff
The Old Man of the Mountain
Elsa Martinelli
The Woman with the Whip
Grégoire Aslan
Achmed Abdullah
Massimo Girotti
Nicolo, Marco's Father
Folco Lulli
Spinello, Venetian Merchant
Guido Alberti
Pope Gregory X
Jacques Monod
Nicolo de Vicenza, a Knight Templar
Miloje 'Mića' Orlović
Matteo, Marco's Uncle