Lionel Barrymore
Julian Northrup aka Gramps
Cedric Hardwicke
Mr. Brink
Beulah Bondi
Nellie Northrup aka Granny
Una Merkel
Marcia Giles
Bobs Watson
Pud Northrup
Nat Pendleton
Mr. Grimes
Henry Travers
Dr. Evans
Grant Mitchell
Mr. Pilbeam
Eily Malyon
Demetria Riffle
James Burke
Sheriff Burlingame
Charles Waldron
Reverend Murdock
Ian Wolfe
Charles Wentworth
Phillip Terry
Bill Lowry
Truman Bradley
James Northrup
Dorothy Adams
Florist (uncredited)
Barbara Bedford
Mrs. James Northrup (uncredited)
Sonny Bupp
Boy in Tree (uncredited)
Hans Conried
Man in Convertible (uncredited)
Howard Hickman
Chief Surgeon (uncredited)
Dickie Jones
Boy in Tree (uncredited)
George Lloyd
Chief of Police (uncredited)
Ted Oliver
State Trooper (uncredited)
Doris Rankin
Mrs. Burlingame (uncredited)
Harold Schlickenmayer
First Stretcher Bearer (uncredited)