Hugh Jackman
Gabriel Van Helsing (voice)
Robbie Coltrane
Mr. Hyde (voice)
David Wenham
Carl (voice)
Grey DeLisle
First Victim (voice)
Dwight Schultz
Dr. Jekyll (voice)
John DiMaggio
Coachman (voice)
Scott Mosenson
Palastwache (voice)
Alun Armstrong
Cardinal Jinetta (voice)
Roger L. Jackson
Gentleman (voice)
Julia Fletcher
Lady (voice)
Tress MacNeille
Queen Victoria (voice)
Tara Strong
Young Victoria (voice)
James Arnold Taylor
Narrator (voice)