Nathan Fillion
Bill Pardy
Michael Rooker
Grant Grant
Elizabeth Banks
Starla Grant
Gregg Henry
Jack MacReady
Tania Saulnier
Kylie Strutemyer
Don Thompson
Wally
Brenda James
Brenda Gutierrez
Jennifer Copping
Margaret
Jenna Fischer
Shelby
Haig Sutherland
Trevor
William MacDonald
Mr. Strutemyer
Iris Quinn
Mrs. Strutemyer
Matreya Fedor
Emily Strutemyer
Amber Lee Bartlett
Jenna Strutemyer
Xantha Radley
Uptight Mom
Dustin Milligan
Drawing Boy
Lloyd Kaufman
Sad Drunk
Zak Ludwig
Gina Kid
Tom Heaton
Tourneur
Mary Black
Woman in Basement
Ben Cotton
Charlie
Lorena Gale
Janene
Dee Jay Jackson
Dwight
Nicholas Podbrey
Diseased Grant part 1
Malcolm Scott
Dude Joining Grant
Darren Shahlavi
Brenda's Husband
Kathryn Kirkpatrick
Karaoke Woman
Corb Lund
Lead Singer
Michael Cromien
Fitzgibbon
Robert Musnicki
Diseased Leader
Stephen Park
Gleeked on Guy
Nicholas Podbrey
Diseased Grant #1
Jeny Cassady
Diseased Grant #2
Alette Falle
Diseased Grant #3
Matt McInnis
Head-Shot Norman
James Gunn
Hank (uncredited)
Magda Apanowicz
Friend (uncredited)
Rick Morwick
Truck Driver (uncredited)
Rob Zombie
Dr. Karl (voice)
Mark Torgl
Melvin Junko (Archive footage)