Martin Lawrence
Malcolm Turner / Big Momma
Marisol Nichols
Liliana Morales
Kevin Durand
Oshima
Dan Lauria
Crawford
Kat Dennings
Molly Fuller
Josh Flitter
Stewart
Zachary Levi
Kevin Keneally
Jascha Washington
Trent
Jeanene Fox
Yasmeen
Mark Moses
Tom Fuller
Chloë Grace Moretz
Carrie Fuller
Emily Procter
Leah Fuller
Nia Long
Sherri
Lisa Arrindell
Danielle (as Lisa Arrindell Anderson)
Bryan James Kitto
Trent's Friend
Luke Ramsey
FBI Agent #1
Lonnie Lamont
FBI Agent #2
Marcus Lyle Brown
Erskine
Mehera Blum
Fuller's Secretary, Lucy
Shanna Moakler
Petra
Yuji Okumoto
Parsons
Yvonne Landry
Isabella
Lisa Arrindell
Danielle
Wendy Braun
Coach Bonnie
Ann Mahoney
Coach Lisa
Deneen Tyler
Tassie
Max Van Ville
Chad
Sean Lampkin
Cabbie
William Ragsdale
Bob
Kelly Dowdle
Surf Shop Girl
Jessica White
Bra Model
Amy Morris
Spa Susan
Michelle Parylak
Spa Joanne
Deena Dill
Spa Crystal
Paige Butcher
Background Model
Lucy Wolvert
Background Model
Tim Soergel
Speedo Guy
Jessica Anderson
Bikini Girl
Breanna Startzel
Girl in Bikini
Preston Shores
Andrew
Trevor Shores
Andrew
Sarah Joy Brown
Constance
Adrian Staton
Sandy (uncredited)